We changed to this hotel after spending the first few nights at the Tacarcuna lodge, which was also fine but very limited in resources (breakfast extremely plain, poor security for rooms, and surrounded by a plaza that blared out music at top volume 24/7). Coming to Hotel Nautilos was very relaxing in comparison, you have the advantage of the sea breeze which is absolutely essential as temperatures go up to 40 degrees celcius, rooms are clean and well equipped, staff were very friendly, and they arranged buffets on the beach and other events that you can take part of if you wish. There was also a pool (yet never cooling because of the temperatures) and we had a beautiful view from our room overllooking this and the beach, which is right outside the hotel.
Tip: if you stay here, also visit the Coco Loco shed on the beach and have a beautiful rum and coconut drink (in a coconut) overlooking the sea.
The staff at the hotel were also the friendliest and most professional tourism personnel we came across in Capurganá. Apart from them, we had quite a horrible week arguing with rude locals who constantly try to charge you three times the price for everything, or charge you for things you do not have to pay (be aware: you do not have to pay for overweight at the docks if you have some, that would be with the airport), simply for being foreigners. Colombians in general treat their tourists very badly, using them as money banks, but this experience literally took the price. Be on your guard, and if you're not prepared to argue (or have the spanish to do so), I would not recommend going, the destination is not worth it. The beautiful parts to the area are the islands around capurganá, including crossing over to Panama, Capurganá should just be used as a stop over to get to these.