Dushanbe is not an easy city to navigate, and it is even tougher you are a first timer and do not speak the local language. And forget about any help from the tourist offices, which is non existent, nor the Police, who are more interested in giving traffic tickets to motorists, than to care anything for you.
ATLAS offer free airport round-trip transfer, and for certain package, free transfer to the city centre. The receptionists and Manager speak good English and does gave reliable tips and advice. The place is secure and the room is well furnished, Yes, it is a bit expensive for Tijikistan, there are many B&B offer much lower rate. but over all, I had a good stay and the service deserve the high price.
The included breakfast is very very good.
On the Con side, its a bit far from the city, though is near the airport. Public transport like shared taxis are challenging if you do not speak Tijik. The hotel is off the mainroad, an the side street is poorly lit, though its safe but it does give you a sense of anxiety.