I would emphatically recommend Manitra as a guide in Madagascar. I came to the country for a week, and spent ~4 days with Manitra and a driver, visiting Andasibe and Ranomafana, with stops in Antsirabe and Ambositra along the way.
His English is excellent, which matters quite a bit if you want to maximize what you learn about the country and the sites. Perhaps more importantly, he's a broadly informed and experienced guy, who once did a Fulbright scholarship at NYU, and was able to share much more context on Madagascar's history, politics, tribal structure etc. Well beyond a basic review of natural features, or lemur species and habits. And, since Madagascar is fairly large, and the roads are extremely poor, you end up doing lots of long drives at 20 - 40 mph, so the quality and range of car conversation is important.
And of course, the tour itself was well-organized - driver, 4x4 in good condition, hotels booked in advance and well-chosen, etc. Manitra was also able to shift the schedule on short notice when my arrival flight was canceled, leading to a half day's delay.
All in, highly recommended. As other reviewers noted, Manitra is a bit more expensive than some of the other quotes you will see (10-20%, based on my experience), but the difference was well worth it.
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