From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

Kissimmee provides the perfect base camp for a date with Mickey. Only a few minutes' drive from the Walt Disney World theme parks, the Florida town is packed with family-friendly activities like mini golf, dinner theatre and ice skating. Get close to nature on an air boat ride through the swamps or pick oranges at a local grove. For a more educational diversion, stroll through the historic downtown or visit the Osceola County Historical Society and Pioneer Museum for a peek into turn-of-the century life.

Escape to Daytona Beach, and discover a destination where new adventures for all ages are around every corner — whether you’re strolling along 23 miles of uncrowded, white-sand beaches or reeling in a new discovery at the Main Street Pier. Greet the morning by soaking in the salt air on a paddleboard tour or by rounding the famed Daytona Beach International Speedway at top speed. Then get a taste of local culture at the Riverfront Shops and the fantastic Museum of Arts & Sciences.

Perfectly positioned at the westernmost tip of sparkling blue Lake Superior, Duluth offers visitors a true escape from the stresses of everyday life and an opportunity to enjoy nature. You can opt for a more leisurely pace: spending time at one of the city's 23 beautiful parks, taking an unhurried drive along the scenic North Shore, bird watching at Hawk Ridge, skipping stones on the Lake with the kids. Or go for a more structured itinerary: the aquarium in the morning, lunch at a sumptuous restaurant on the waterfront plus a tour of the famous Sculpture Walk, then a visit to the historic Railroad Depot in the afternoon. Either way, you are sure to leave Duluth feeling relaxed and refreshed.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

In Sonoma, you can go wine-tasting… or cheese-tasting… or olive oil-tasting… or just let the chefs of the area’s renowned restaurants put everything together for you. Then burn off some of that good food and wine by hiking or biking through redwood forests.

Much of northern Spain belongs to Castile-Leon, an autonomous region surrounded by mountains. Architectural gems like the Romanesque stonework of Segovia's city walls, the Gothic Burgos Cathedral and the dramatic Baroque square in Salamanca are complemented by the area's natural beauty. Parque Natural de las Hoces del Rio Duraton is marked with deep gorges and shelters many birds of prey, while Parque Natural del Lago de Sanabria y alrededores contains the largest glacier lagoon on the Iberian Peninsula.

Once a shipbuilding city, Newcastle's flashier claim to fame is nightlife. Throw in a heap of premium restaurants serving foods from all over the world and it's no wonder young partiers choose to blow their hard-earned (or not-so-hard-earned) cash in Newcastle. While these amenities are certainly a draw for the hipsters and culture-seekers, it's the locals that make Newcastle a truly special place to visit. "Geordies," as they are often called, embody the pride, industriousness and resilient spirit of their city.

Porto Alegre is a cultural heavyweight—from museums to an edgy music scene, the city overflows with creativity. The best show of all may be sunset on the Guaiba River, which brings a nightly audience to the waterfront.

California’s desert regions fascinate visitors with the unexpected. Vast expanses, wide salt flats and ghost towns are on full display in In the quintessential desert at Death Valley National Park. Visit Joshua Tree National Park to see both the Mojave and Colorado desert landscapes, where wildflower blooms offer a spectacular sight every spring. Don’t miss the sculpture gardens and hiking trails of Anza-Borrego Desert State Park.