The largest island along Brazil's coast and, literally, a “beautiful island,” Ilhabela offers visitors almost 40 kilometres of pristine beaches and a tropical island's worth of hiking trails, waterfalls and even a nascent party scene. At 207 kilometres from the city of São Paulo, Ilhabela can get crowded, so try to get your beach time in during the work week.

German-inspired architecture adds a quirky Alpine twist to this resort, where high-altitude pine forests offer a wonderfully cool escape from the lowland heat. Add emerald-green peaks as a backdrop, and Campos do Jordao becomes a tropical mountain stunner.

NNipping at the ankles of the Andes, San Carlos is a world-renowned ski destination, set in a landscape offering all the natural wonders of Argentina. Visitors can experience snow, lakes and peaceful beaches, along with vibrant nightclubs and gourmet cuisine. Throughout the year, the area hosts several music festivals, art exhibitions, expositions and conventions.

Villavicencio is a hub for cattle farming, and the area abounds with cowboys. You could stay on a ranch for a night or two before moseying off to the more oft-visited grassland plains of Los Llanos. If you care to stay awhile, Villavicencio has plenty of opportunities for outdoor activities and eco-tourism. Don’t miss the Caño Cristales, a beautifully multi-colored river filled with vibrant plants and minerals that’s appropriately nicknamed “The Liquid Rainbow.”

Cartagena, a gorgeous fishing village on Colombia's Caribbean coast, has excellent beaches, a historic old town (that's entirely walkable) and beautiful colonial architecture. It's also one of the safest places in the country, so it's no wonder it's a popular port of call for cruise ships. Need a break from exploring the cobblestone streets? Stop at an outdoor cafe for excellent pastries and people-watching.

This former fishing village on Portugal’s southern coast has become a popular resort. Spend a day on Alvor’s main beach, or find one of the smaller, secluded coves along the coastline. In the evening, stroll through the town’s narrow cobblestone streets, dine on fresh local seafood, and enjoy live music at one of the many lively bars.