Let the Gulf Shore breeze carry you to a weekend of sun-kissed fun. The Tampa-St Pete area is Florida's second-biggest metropolitan area. Not as flashy as Miami or as crowded as Orlando, the region has grown as a tourist destination, and it's easy to see why: miles of waterfront, sandy beaches, cultural attractions and exciting amusements. Busch Gardens has been drawing visitors for years, but the city also has another zoo, an aquarium and several major museums for those who need some time in the shade.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Beyond its epic theme parks and perfect weather, Orange County is celebrated for outdoor dining, entertainment and beach-bound adventure. Treat yourself at South Coast Plaza for the finest in luxury shopping and superlative restaurants. Spend an afternoon aboard a whale watching cruise in Newport Harbour, or cast a reel from the Huntington Beach Pier. Stop to smell the flowers at the Sherman Library and Gardens, or explore Laguna’s vast variety of boutique shops along the Pacific Coast Highway.

Known as the home of “the happiest place on Earth,” there’s more to Anaheim than thrilling theme parks. Bring your appetite to the Anaheim Packing District and Centre Street Promenade for some eclectic eateries and award-winning craft breweries. Explore the latest exhibits at the Muzeo Museum and Cultural Centre. Enjoy live music at the all-new House of Blues, now at the Anaheim GardenWalk.

The soft sea breeze, the crystalline waters and the tranquility are a few of the most important traits of La Pineda Beach. Almost four kilometers of beach lines the seafront promenade of this coastal resort. La Pineda has some of the cleanest, safest and environmentally best-managed beaches, as the Blue Flags regularly awarded by the European Foundation for Environmental Education attest. A wide range of activities can be organized right on the beach.