Trentino-Alto Adige is made up of two provinces, the Italian-leaning Trento (or Trentino) in the south and the Germanic-leaning Alto Adige (or Südtirol, and also called Bolzano-Bozen, just to keep things interesting) in the north. Home to numerous picturesque towns, castles and historic sights, the main attraction here is the mountains. The stars of these are the Dolomites. Outdoor adventure opportunities abound year-round, with skiing, climbing and hiking among the most popular pursuits.

Stroll Las Ramblas and enjoy Barcelona's unique blend of Catalan culture, distinctive architecture, lively nightlife and trendy, stylish hotels. You'll find Europe's best-preserved Gothic Quarter here, as well as amazing architectural works by Gaudi. La Sagrada Familia, considered Gaudi's masterpiece, is still under construction (your entrance fee helps to fund the project). Feel like a picnic? Look no further than the rambunctious La Boqueria market, where you can stock up on local delicacies.

Everyone who visits Paris for the first time probably has the same punchlist of major attractions to hit: The Louvre, Notre Dame, The Eiffel Tower, etc. Just make sure you leave some time to wander the city’s grand boulevards and eat in as many cafes, bistros and brasseries as possible. And don’t forget the shopping—whether your tastes run to Louis Vuitton or Les Puces (the flea market), you can find it here.

In progressive Berlin, the old buildings of Mitte gracefully coexist with the modern Reichstag. Don't miss top historic sights like the Berlin Wall, Checkpoint Charlie, the Brandenburg Gate and Potsdamer Platz. The city's great zoo makes for a fun break from touring the staider attractions.

Amsterdam is truly a biker’s city, although pedaling along the labyrinthine streets can get a little chaotic. Stick to walking and you won’t be disappointed. The gentle canals make a perfect backdrop for exploring the Jordaan and Rembrandtplein square. Pop into the Red Light District if you must—if only so you can say you’ve been there. The Anne Frank House is one of the most moving experiences a traveller can have, and the Van Gogh Museum boasts a sensational collection of works.

From Shoreditch’s swaggering style to Camden’s punky vibe and chic Portobello Road, London is many worlds in one. The city’s energy means that no two days are the same. Explore royal or historic sites, tick off landmarks from your bucket list, eat and drink in exclusive Michelin-starred restaurants, enjoy a pint in a traditional pub, or get lost down winding cobbled streets and see what you stumble across – when it comes to London, the possibilities are endless.

The geographical heart of England, Birmingham began life as a sixth- century Anglo-Saxon village. Today, much of this city of over a million dates back to post-WWII redevelopment in the 1950s and 60s. Cutting edge museums and galleries, innovative theatres and excellent shopping have contributed to Birmingham's appeal as a weekend break destination. Don't miss the Balti Triangle, home to the Pakistani food in the UK, the hopping bars and cafes of Gas Street Basin, or the National Sea Life Centre.

Leeds, a city in West Yorkshire, England, was one of the leading centers of industry in Victorian England. The Leeds City Museum is a great place to brush up on local history, and many TripAdvisor travelers say no visit to town is complete without exploring the Royal Armouries. You’ll also find lovely parks and a lively restaurant scene, with many eateries specializing in international cuisine.

Cumbria's valleys and fells (as the low mountains are known) are home to idyllic villages, high moorlands and picturesque lakes. Literary buffs will enjoy Wordsworth's Dove Cottage (go in March to see daffodils), and if you've got kids in tow, visit The World of Beatrix Potter. Or just enjoy a leisurely drive through beautiful scenery.