Perched on the banks of the dreamy Lácar Lake, San Martin de los Andes is a Patagonian paradise. Birdwatchers flock and flutter to the annual South American Bird Fair, while thrill seekers love to kayak, ski, or mountain bike along the gorgeous landscape. Arts and crafts shops and artisan food producers will delight visitors that love a sensory sampling of local cultures.

Ouro Preto is a former colonial mining town with beautifully preserved Baroque architecture and quaint cobblestone streets. It has been designated a UNESCO World Heritage Site. It earned recognition during Brazil's Golden Age as a centre for gold mining and prosperity in the 18th century. Today it is a popular tourist destination.

Antigua has hundreds of beaches, from the bustling Pigeon Point to the kitesurfing paradise of Jabberwock Beach. It's fun to mix it up—a day spent in a secluded cove, another spent people-watching at a tourist magnet. When you’re tired of sun and sand you can shoot ‘em up at Reservoir Range, where archery and air pistols are a fun way to work out any lingering pre-holiday stress. A tour of the Antigua Distillery is a spirited way to experience a true taste of the island.

Sure, you can leave the sunny sands in favor of a crocodile watch or horseback ride, but when the main strand is called Seven Mile Beach, it's clear what draws most visitors to Negril. Depending on how much sun you want, you're welcome to go topless or even sunbathe in the buff in some places.

More than 30 miles of beaches plus a wealth of cultural and historic institutions make this island a Gulf of Mexico holiday hot spot. If you go, don't forget your walking shoes: With 14 museums and 20 art galleries, plus several historic homes and mansions, there's a lot of ground to cover. Armchair pilots will love the Lone Star Flight Museum and those with more of a nautical interest can check out the Texas Seaport Museum. Families will enjoy the many child-friendly attractions, including Moody Gardens, with its replica of a tropical rain forest. It's easy to get caught up in all the activities, but don't forget to spend some downtime in the sun and on the beach.