Halfway between San Francisco and L.A., San Luis Obispo can be a relaxing getaway or a buzz of activity. For serenity, pack a lunch and head to one of dozens of wineries or take a drive to the beach for a leisurely swim. For a dose of history, visit the heart of the city at the beautiful Mission San Luis Obispo de Tolosa. Kids will love the Children’s Museum or Skate Park. Be sure to stroll along the creek downtown, where there are breweries, wine bars, restaurants and shopping for all tastes.

Monterey offers a host of historic attractions from Cannery Row to the famous Monterey Aquarium. This incredible sliver of oceanfront offers an amazing bounty of things to do, with marine, floral and vine-fresh delights to savour. Monterey-Salinas Transit and Amtrak let you take your eyes off the road. Charming towns, world-class golf courses and idyllic inns lie at the edge of the glittering Pacific. Whether you're looking for calm or noisy beachside fun, the Monterey Peninsula has it in buckets.

Estes Park is located 7,522 feet above sea level, nestled in the heart of the Colorado Rocky Mountains. Shops, galleries and boutiques line the main street, which has a quaint, small-town ambiance. Exceptional outdoor adventures await both families and enthusiasts. Wildlife sightings, including elk and big horn sheep, are prevalent. Estes Park is the basecamp for adventures in Rocky Mountain National Park, where world-class hiking, rock climbing, backcountry skiing and scenic drives abound.

Home to the University of Florida, the largest and oldest university in the state, as well as the Santa Fe Community College, Gainesville is a hub of education and culture. Perhaps due to its strong student population, the city is also at the heart of independent music in Florida, having produced numerous musical acts from a variety of genres. The natural surroundings, including parks, lakes and the adjacent Paynes Prairie State Reserve provide a green getaway from the bustle of city life.

From ornate mansions to ocean views, this charming city - the largest in Maine - will enchant you. Saunter down the brick sidewalks and cobblestone streets of the revitalized Old Port District, where you can browse through bookstores, explore craft shops and eat to your heart's content. Visit the Portland Head Light, which dates back to 1791, and is the oldest lighthouse still in continuous use in the U.S. The great poet Henry Wadsworth Longfellow is the city's native son, and you can visit his childhood home, the Wadsworth-Longfellow House. With kids in hand, enjoy the highly interactive Children's Museum of Maine. And then go next door to the calmer Portland Museum of Art, a small, but eclectic museum with Impressionist works, Maine landscapes by Homer and Wyeth and other collections. Land or sea is an option here, so if you're tired of the street life, take one of the popular scenic cruises or whale watches, or hop on a ferry to the islands in Casco Bay. At the end of the day, and without kids in hand, unwind and rest your tired feet at one of the city's brewpubs.

This beautiful fishing village is a Nicaraguan gem, a magnet for surfers and sunbathers. At night, the beach still pulses with activity, thanks to a few popular beachfront bars and nightclubs. Surf clubs abound—catch a wave with an expert instructor if you’re a hang-ten rookie, trying to hang with the surfer big boys.