Sitting on the south shore of Rhode Island, the town of Westerly is a quiet residential community in the winter, swelling in the summer to accommodate tourists eager to explore the local beaches, Narragansett Bay and the Rhode Island Sound. Just over the border from Connecticut, Westerly is conveniently located to the Aquarium at Mystic, as well as the Mohegan Sun and Foxwoods Casinos. Nearby, the picturesque village of Watch Hill features ocean views, ice cream shops, and craft boutiques.

Surrounded on all sides by snow-capped peaks and set at the narrow head of a deep valley, Ouray touts itself as the "Switzerland of America." With no nearby ski area to attract the tourism of other alpine Colorado towns, Ouray has kept much of its authentic turn-of-the-century charm. The whole town is registered as a Historic District and includes many buildings on the National Register of Historic Places. Its free Ice Park attracts amateur and pro ice climbers from around the world.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."