Getting sick on holiday is a major drag, but if you have to be under the weather, Montpellier is an ideal place to do it. People have studied medicine here for centuries—the Moors established medical schools in the 9th century, and the Université Montpellier’s school of medicine was founded in 1220. Once the local docs give you a clean bill of health, explore the cathedral, mansions and opera house.

This beautiful fishing town on the Mediterranean Sea glimmers with sunshine and charm—so much so that Vincent van Gogh captured the streets and seascape of Saintes-Marie-de-la-Mer. In between lunching and shopping, visit the monolithic Church of Three Saints, a stone Romanesque church that was built in the 12th century. That, plus museums and bullfight arenas, will stimulate your cultural yens. Savour fresh fish and plump shellfish at any one of Sainte-Marie-de-la-Mer’s exquisite cafes and restaurants.

Once one of the great Roman cities, Nimes’ storied past takes centre stage in the modern city, with ancient ruins, medieval monuments, and archaeological museums all presided over by a remarkably preserved Roman amphitheater.

Surrounded by golden sands, oyster-filled lagoons, and ancient salt flats, the Mediterranean port town of Sete offers a tranquil change of pace from the busy resorts of the Languedoc. Effortlessly photogenic, the picturesque canals are lined with fishing boats, traditional markets, and seafood restaurants.

It's easy to understand why Vincent Van Gogh was so charmed by Arles, with its sun-kissed stone houses, cobbled squares, and Roman ruins. Set on the banks of the Rhône River, the city also harbours a robust contemporary arts scene.

In the heart of Calanques National Park, Cassis offers visitors a glimpse of life in a quaint Provencal fishing village. Hop on a sightseeing boat to experience the Cassis Calanques by water, or enjoy the turquoise coastline from a pebble beach. There’s much to explore by foot, too. Admire the pastel-colored houses lining the picturesque harbor, drift into the village’s charming shops and cafes, and take in the scenic views of the French Riviera from the many vantage points along the way.

Stroll Las Ramblas and enjoy Barcelona's unique blend of Catalan culture, distinctive architecture, lively nightlife and trendy, stylish hotels. You'll find Europe's best-preserved Gothic Quarter here, as well as amazing architectural works by Gaudi. La Sagrada Familia, considered Gaudi's masterpiece, is still under construction (your entrance fee helps to fund the project). Feel like a picnic? Look no further than the rambunctious La Boqueria market, where you can stock up on local delicacies.

Liguria, or the Italian Riviera, boasts a bounty of beaches and resort towns, such as tiny Portofino and stylish Rapallo. Hiking trails lead from Portofino to the villages of Cinque Terre. The Riviera of the Setting Sun runs north from Genoa to the French border. Connected by an extensive rail network, most towns are an easy day trip from one another. Genoa is the region's principal city and is home to the famous Cathedral, the Palazzo Reale and an excellent aquarium.

Brittany’s charming capital, Rennes is home to enough timber-framed houses and cobblestone streets to make you feel transported back to medieval France. Far from sleepy, however, the university town boasts art museums, sidewalk cafés, and the verdant Parc du Thabor.

From Shoreditch’s swaggering style to Camden’s punky vibe and chic Portobello Road, London is many worlds in one. The city’s energy means that no two days are the same. Explore royal or historic sites, tick off landmarks from your bucket list, eat and drink in exclusive Michelin-starred restaurants, enjoy a pint in a traditional pub, or get lost down winding cobbled streets and see what you stumble across – when it comes to London, the possibilities are endless.