Day-trip distance from Buenos Aires, the Tigre River Delta offers porteños (Buenos Aires residents) and tourists alike a playground for everything from horseback riding and hiking to fishing and swimming. Comprised of hundreds of tiny islands, the Tigre is about 20 miles northeast of Buenos Aires and is reachable from the city by trains, then by boat from the train station. While the main attraction here is the delta itself (formed where five rivers come together), you’ll also find a Naval Museum, restaurants and playgrounds for kids. Several tour companies offer day-trip excursions to the Tigre River Delta—but visitors also can book stays in area bed & breakfasts and adventure lodges.

Most travelers come to Uyuni to visit some of the world’s most unusual terrain—the Salar de Uyuni. This is the world’s largest salt flat, and you’ll want to bring a camera for surreal photos of salt-encrusted ground, geysers, and multicolored lakes.

Ten million people call vibrant, passionate, sprawling Bogota home. The energy of this metropolitan heart of Colombia is in part fueled by its hundreds of eclectic and authentic dining hot spots, fantastic wines, and frequent foodie festivals. Ask the locals where they like to eat, then walk off your empanadas and aji with a stroll through the historic district of La Candelaria or during an indulgent shopping adventure on the North Side.

White beaches, a sparkling sea, a strawberry daiquiri in hand—what more do you need in a holiday? Marco Island brings visitors the best that the Ten Thousand Islands have to offer. Scavenge for seashells or hit the links for a sunny session of golf. Explore the Everglades in a swamp buggy or enjoy a rejuvenating nature hike at the Rookery Bay Reserve.

Looking for world class powdery white quartz sand beaches, 100 golf courses within driving distance, and an endless selection of cultural and family activities? Siesta Key is the laid-back beach town that goes above and beyond. Right nearby in Sarasota, you'll find museums, art, wildlife, circuses, opera, ballet, symphonies, theater, film festivals, botanical gardens, baseball spring training... the list goes on.

From the 27th-floor observation deck of the new Capitol building, you can take in the beauty of this lovely city on the Mississippi, at one time the heart of plantation country. Stately antebellum mansions line the river, some now bed and breakfasts, others offering tours. A visit to the Louisiana State University (LSU) Rural Life Museum will transport you to a 19th-century plantation. The 34-storey Capitol, built in the 1930s by controversial Governor Huey P. Long, and the building in which he was assassinated, contrasts sharply with the Old State Capitol, a Gothic Revival-style castle perched high on a bluff. A college-town atmosphere permeates this friendly city, home to LSU and Southern, the largest African-American university in the USA. You'll find many historic sites, museums and galleries to explore, some on the LSU campus. For the more outward bound, there are great running and hiking trails. The city's unofficial motto is "Let the good times roll", and roll they will as you dine on spicy Cajun food, sample a riverboat casino or gaze out at the mighty Mississippi.