Stretching 126 miles south towards Cuba, the stunning Keys are a perfect escape. Highlights along the way include Key Largo, Islamorada, Marathon, Big Pine Key and the irrepressible Key West. Come face to face with an amazing array of fish while snorkelling, diving or fishing in the warm turquoise waters. Creeks, coral and costumed shows are other lures along the way. Highway 1 is a spectacular ribbon tying together the islands and atolls of this paradise between the Gulf of Mexico and the Atlantic.

Key Largo's spectacular Sandspur and Caloosa Beaches are a part of protected area Bahia Honda. This divine duo of sandy beaches, with their coconut palms and year-round warm waters, offer marvellous swimming, snorkelling and kayaking in their calm waters. Sandspur is especially popular with families.

The island community of Marathon in the Florida Keys is a tropical getaway for your whole family. It maintains a retro, nautical atmosphere with family-friendly festivals and attractions. Activities include dolphin swims, snorkeling, and boating. Seafood festivals are scheduled throughout the year, and plenty of local restaurants feature fresh catches. Fishing is ideal off the pristine Sombrero Beach. Visit Crane Point to hike to the preserved home of a 20th century settler family.

Whether you're into sport, sunshine or salsa, Miami sizzles all year round with exciting entertainment venues and attractions, world-class hotels and restaurants, great beaches and a nightlife that never sleeps. While South Beach, with its hip nightclubs and pastel-hued buildings, gets all the press, other sections of Miami are just as hot and offer culture, recreation and more. Spend the day soaking in the sights and sounds of Little Havana or soaking up the rays at Haulover Beach Park. Explore the Art Deco District or take the children to the zoo. At the end of the day, chill out at one of the area's bars and nightclubs. In Miami at night, the day is just beginning.

At the shore in Miami Beach, visitors can swim, surf and jet ski in the warm and crystal-clear Atlantic waters. You can also nap on the white sands, work on a tan or simply watch the beautiful people, especially at South Beach, a favourite of models and celebrities.

Key West has great nightlife—and a perfect cover story for someone who wants to enjoy it. A Hemingway fan simply must toss back a few at their hero’s favourite bar! You’re not reliving Spring Break, you’re immersing yourself in great American literature. Yeah. That’s the ticket.

With 2.5 miles of beautiful beaches, an iconic pier and lovely ocean vistas, Lauderdale by the Sea is a small community that attracts visitors from around the world. Here low-rise downtown buildings and mid-century modern architecture exude old Florida charm, even as they celebrate the town’s present-day connection to the ocean — most hotels, restaurants and shops are just a few minutes’ walk from Anglin’s Square, a charming oceanfront gathering place.

Sharing its warm, lapping waters with its Gold Coast neighbors Boca Raton, Fort Lauderdale and Hollywood, Pompano Beach lives up to the promise in its name; miles of beach along the temperate Gulf Stream await the sun-thirsty traveler. Overhead Goodyear's Spirit of Innovation blimp patrols the blue skies. The surrounding area is home to enough links courses to keep an intrepid golfer very busy for weeks. Miami and Gold Coast attractions, sports and entertainment are all within easy access.

Culture-seekers will be charmed be La Isla's heritage and history, from Old San Juan's charms to folk art and festivals in the outlying towns. You can drive round Puerto Rico in a day, but take your time. Coffee plantations, colonial towns, beaches, bars and restaurants wait to be explored. Old San Juan, with famed Castillo de San Felipe del Morro, is an atmospheric place to wander. Experience life at a different pace by rainforest hiking, scuba diving or swimming Vieques' glowing bioluminescent lagoon.

Vibrant and packed with Victorian mansions, Costa Rica's rowdy, bustling capital was built on the profits of the coffee trade and working "golden bean" plantations still surround the city. Try freshly roasted local beans at Mercado Central. For shinier gold, visit the Museo del Oro. Many renovated landmarks now house stylish hotels. Usually viewed as a hub, rather than a destination, nightlife is concentrated in Spanish village-inspired El Pueblo. Don't miss the elegant 1897 National Theater.

Flanked by lakes, mountains and intriguing rock formations, Grand Junction offers a different side of Colorado. Mild weather year-round creates an agricultural oasis for 22 different wineries. Mountain bike along winding desert trails, wine and dine next to majestic rivers, and peruse a variety of shops, galleries and boutiques. For breathtaking natural beauty, don’t miss Grand Mesa National Forest and Colorado National Monument’s 23-mile stretch of scenic overlooks.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

San Diego embodies laid-back California culture, complete with a Boardwalk, surfing communities, and outstanding Mexican food. Breathe in the fresh ocean air at Sunset Cliffs Natural Park, then gobble down a fresh fish taco at a La Jolla seafood joint. The naval aircrafts at the USS Midway Museum will have you standing at attention. A free Sunday concert at the Spreckels Organ Pavilion is the perfect way to unwind after a Saturday night bar-hop in the thumping Gaslamp Quarter.

Surrounded by breathtaking scenery, majestic mountains, rushing rivers, rolling foothills and dramatic landscapes, Ashland is a gorgeous little city with an arts scene as vibrant as its setting. Ashland hosts festivals for all seasons, with Christmas celebrations and the Oregon Shakespeare Festival in winter, a film festival in the spring, classical music festival in summer and wine tasting celebrations in the autumn.