Amsterdam is truly a biker’s city, although pedaling along the labyrinthine streets can get a little chaotic. Stick to walking and you won’t be disappointed. The gentle canals make a perfect backdrop for exploring the Jordaan and Rembrandtplein square. Pop into the Red Light District if you must—if only so you can say you’ve been there. The Anne Frank House is one of the most moving experiences a traveller can have, and the Van Gogh Museum boasts a sensational collection of works.

Mostly jutting northward from its largest city of Amsterdam and its capital of Haarlem, the Noord-Holland region has much more to offer beyond those two wonderful cities. At Muiden is the magnificent Muiderslot Castle, as if it stepped out of a fairy tale. Showing more wear but no less interesting is Brederode Castle at Santpoort. At Zaanstad is Zaanse Schans, one of Holland’s top tourist destinations and a family-friendly open air museum of windmills, traditional buildings, crafts and shops.

Holland's most modern city began as a fishing village in the 13th century. It was developing into an industrial and trading power when German bombers destroyed the city centre and harbour in 1940. However, Rotterdam's unique architecture now brings many visitors to cycle around this urbane, cosmopolitan city. Old Dutch-style houses can still be found in historic Delfshaven, from where the pilgrims set sail in 1620. Cultural offerings ranging from the summer carnival to classical music can compete with those of Amsterdam.

Eindhoven is one of the oldest cities in the Netherlands, but you’d never know it from the high-tech industry and cutting-edge design it’s currently known for. If you have kids obsessed by all things wheeled, they will love the trucks at the DAF Museum.

If you live, eat and breathe skiing, Obertauern is your paradise—its own little mountaintop microcosm where you can literally walk (er, ski) out the door of your charming lodge or B&B and directly enter the slopes. Feeling ambitious? Complete a “Tauern Circuit” of the ski lifts and slopes that encircle the village. The restaurants and lodges offer merry après ski rejuvenation.

Dubbed the Queen City, Charlotte reigns over a 300-square-mile (482-square-kilometre) hodgepodge of neighbourhoods that spin out from the banks of the Catawba River. From brewery-heavy art districts to historical corridors dripping in charm, consider Charlotte a crowd pleaser.