Destin is located on Florida’s Emerald Coast, which gets its name from its beautiful, clear green water. Beaches here have extremely fine, soft sand, so if you’re a beach-walker or your kids enjoy building sand castles, this could be a great destination for you.

It's called the Live Music Show Capital of the World-- on any given day, almost 90 music, magic and comedy shows run at 50+ theatres. You might catch into Tony Orlando, the Osmonds or Marty Stuart, all regulars. (Think Las Vegas without the casinos and people drinking margaritas-by-the-yard at 10 am.) Between shows, enjoy nature in the Ozarks-- you'll find great fishing, hiking, biking and water sports in the area.

It’s not just for spring-breakers. Cancun, with its golden beaches and perfect climate, is the premiere coastal destination in Mexico. And while there is certainly a 365-day party available for college students, resorts cater well to families and to those seeking solitude. This Yucatan paradise is also the gateway to the ruins of Tulum and Chichén Itzá.

From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Known as the home of “the happiest place on Earth,” there’s more to Anaheim than thrilling theme parks. Bring your appetite to the Anaheim Packing District and Centre Street Promenade for some eclectic eateries and award-winning craft breweries. Explore the latest exhibits at the Muzeo Museum and Cultural Centre. Enjoy live music at the all-new House of Blues, now at the Anaheim GardenWalk.

If watching the sunrise from atop a 10,000-foot volcano, swimming under waterfalls, hiking through craters and luxuriating on white-, red- and even black-sand beaches sounds like paradise, then Maui awaits. Maui is the place to surf and windsurf. Or hop a catamaran to scuba and snorkel on Molokini Island, a crater emerging from the sea that hosts a wealth of marine life. Golf, fine dining, a winery, museums and sipping a mai tai on the beach round out the perfect tropical holiday.

Say aloha to tropical breezes, oceanfront luaus and iconic Diamond Head on Oahu, the most populated Hawaiian island. Follow in the footsteps of surfing forefather Duke Kahanamoku on Waikiki Beach, visit the royal quarters of Iolani Palace and tour Pearl Harbor. Sample hot malasadas (local doughnuts) and shaved ice while shopping for vintage floral-print shirts on Honolulu's Kapahulu Avenue. Get off the tourist trail with a hike to Makapuu Lighthouse on the South Shore. You can even learn to hula.

Mangroves meet sandy beaches in laid-back Maragogi, a growing town whose locals and visitors both head to the sea for sunset drinks and socializing. The most sought-after treasures are off the coast, where the Gales de Maragogi marine reserve shelters crystal-clear ponds, coral reefs, and colorful fish.