Buffalo is being reborn as a mecca for art, architecture, history, culture, dining and entertainment. Experience Frank Lloyd Wright’s stunning Darwin Martin House Complex and world-class modern art at the Albright-Knox Art Gallery. Relive part of the city’s incredible history at the Theodore Roosevelt Inaugural National Historic Site. Explore the emerging Canalside waterfront district, hip Elmwood Village, more than 400 independently owned restaurants (serving our famous chicken wings and more) and nearby Niagara Falls.

Just north of Cancun, this seaside resort community is a far cry from the spring-break crowd. Bordered on one side by the Mexican Caribbean and the other by a wetlands wildlife preserve, the vibe in Playa Mujeres is one of laid-back luxury in a natural, untouched landscape. Unlike many other such tranquil places, Playa Mujeres is not a pain to get to. It's an easy ride from Cancun airport.

Stretching from the fishing village of Puerto Morelos to the biosphere reserve of Sian Ka'an, the Mayan Riviera offers an unforgettable Caribbean coastline experience. Divers and snorkelers will be dazzled by the wrecks of Xcaret and the Puerto Morelos reef. Use a zip line to descend into the sacred subterranean caverns of LabnaHa Eco Park, where you can snorkel an underground river under a canopy of stalactites. The nearby Tulum Monkey Sanctuary will put you in a playful mood.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Spa-goers have flocked to Carlsbad since its mineral spring was discovered in the late 19th century. Today, you can visit the site of the original well, but you can do much more than just "taking the waters"—Carlsbad’s spas offer world-class services.

About an hour south of Los Angeles, Laguna Beach has a spectacular clifftop setting above some of the finest beaches in California. Outdoor enthusiasts can snorkel, scuba dive, body-surf, or hike the trails in nearby Laguna Coast Wilderness Park. A centre for artists, there are a number of special events and festivals,such as the Sawdust Art Festival, Festival of Arts/Pageant of the Masters, Art-A-Fair and Plein Air Painting Invitational. The Laguna Art Museum focuses on California artists. Window shoppers and collectors will enjoy strolling the village’s quaint streets, as well as visiting galleries spotted along Pacific Coast Highway.

A smorgasbord of flavors come from this lofty land in the hilly southeast of Belgium: game, wild boar, venison, smoked ham, the region's famous paté and world-renowned Trappist beers. Primarily located in Belgium, the Ardennes mountains also nudge into France and Luxembourg. Dense forests flank the steep hillsides, and market towns and villages perch on river banks. Spring and summer show this lush area at its best, but cross country skiing opportunities make a good case for winter visits.