Surrounded by one of Germany's largest wine-growing regions, Stuttgart beckons cultural junkies with its acclaimed ballet, opera and philharmonic, while car fans get revved up over the Mercedes Benz Museum. There's more green space than urban sprawl in the festival-friendly city, home to Europe's largest combined zoo and botanic garden, the Wilhelma. The Württembergisches Landesmuseum, in one of the city's oldest structures, traces the area's history from the Stone Age. Buses or metro provide handy transport.

Aix, a graceful, lively city, is known for its thermal hot springs, art schools and universities. Wander the Cours, old town and Quartier Mazarin on foot, stopping at cafés, bookstores and markets. Kids whining? Have them count fountains… Aix reportedly has 1,000 of them.

The small city of Sitges parties big. The nightlife is thumping, the people are gorgeous and the annual Carnival festival is utterly epic. A countercultural touchstone, Sitges is lively and very LGBT friendly. Native food and beverage is sublime—you simply must sample the Malvasia wine, made from grapes descending from Ancient Greece. Don’t miss the Museu Romàntic "Can Llopis" or, if you’re in Sitges in October, the world-renowned Sitges Film Festival, a cinematic extravaganza of horror, sci-fi and fantasy.

Follow the mineral-rich muddy footprints of Herod, Solomon and Cleopatra to the legendary Dead Sea and resorts developed round its adjacent hot springs. This famed health destination, at the world’s lowest dry point, is known for helping with rheumatic and skin problems.

La Palma is a pristine paradise, set against a backdrop of volcanic landscape. Perhaps the best way to experience La Palma’s rugged beauty is a hike through the Caldera de Taburiente National Park or the narrow gorges of Los Tilos. The cool waters of natural swimming hole Charco Azul beckon on a steamy day. The dark sands of Playa Nueva are great for sunbathing and cat naps.

The emirate of Sharjah offers an inviting combination of culture, heritage, art and outdoor activities. Admire the rare artifacts at the Museum of Islamic Civilization, and visit the arts area for a taste of traditional and contemporary art. A walk through the Heart of Sharjah will reward visitors with a glimpse into history, while outdoor enthusiasts can enjoy an exciting 4-wheel drive through the dunes before relaxing on the white beaches or snorkelling through the clear blue waters offshore.

Dubai is a destination that mixes modern culture with history, adventure with world-class shopping and entertainment. Catch a show at the Dubai Opera, see downtown from atop the Burj Khalifa and spend an afternoon along Dubai Creek exploring the gold, textile and spice souks. If you’re looking for thrills, you can float above the desert dunes in a hot air balloon, climb aboard a high-speed ride at IMG Worlds of Adventure or skydive over the Palm Jumeirah.

Kodaikanal has an endangered animal called the grizzled giant squirrel. To us, that alone is reason to book a trip ("grizzled giant squirrel" might be the best animal name ever). Perched on the woodsy southern crest of the Palani Hills, nearly 7,000 feet above sea level, this popular lakeside resort town is a magnet for nature lovers. Wander the peaceful slopes, keeping an eye out for birds, exotic flowers and, of course, grizzled giant squirrels.