At the shore in Miami Beach, visitors can swim, surf and jet ski in the warm and crystal-clear Atlantic waters. You can also nap on the white sands, work on a tan or simply watch the beautiful people, especially at South Beach, a favourite of models and celebrities.

Culture-seekers will be charmed be La Isla's heritage and history, from Old San Juan's charms to folk art and festivals in the outlying towns. You can drive round Puerto Rico in a day, but take your time. Coffee plantations, colonial towns, beaches, bars and restaurants wait to be explored. Old San Juan, with famed Castillo de San Felipe del Morro, is an atmospheric place to wander. Experience life at a different pace by rainforest hiking, scuba diving or swimming Vieques' glowing bioluminescent lagoon.

Flanked by lakes, mountains and intriguing rock formations, Grand Junction offers a different side of Colorado. Mild weather year-round creates an agricultural oasis for 22 different wineries. Mountain bike along winding desert trails, wine and dine next to majestic rivers, and peruse a variety of shops, galleries and boutiques. For breathtaking natural beauty, don’t miss Grand Mesa National Forest and Colorado National Monument’s 23-mile stretch of scenic overlooks.

Vibrant and packed with Victorian mansions, Costa Rica's rowdy, bustling capital was built on the profits of the coffee trade and working "golden bean" plantations still surround the city. Try freshly roasted local beans at Mercado Central. For shinier gold, visit the Museo del Oro. Many renovated landmarks now house stylish hotels. Usually viewed as a hub, rather than a destination, nightlife is concentrated in Spanish village-inspired El Pueblo. Don't miss the elegant 1897 National Theater.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

San Diego embodies laid-back California culture, complete with a Boardwalk, surfing communities, and outstanding Mexican food. Breathe in the fresh ocean air at Sunset Cliffs Natural Park, then gobble down a fresh fish taco at a La Jolla seafood joint. The naval aircrafts at the USS Midway Museum will have you standing at attention. A free Sunday concert at the Spreckels Organ Pavilion is the perfect way to unwind after a Saturday night bar-hop in the thumping Gaslamp Quarter.